Description
Pantoprazole 40mg + Domperidone 10mg Tablets– The fixed-dose formulation is used to treat GERD, heartburn, and peptic ulcer disease. Pantoprazole is a proton pump inhibitor that reduces stomach acid. Domperidone is a prokinetic that increases intestinal motility, helps relieve nausea, and speeds up stomach emptying.
It is a primary choice for diseases that do not respond to PPIs alone. It is also used for functional dyspepsia and acid-related indigestion. The medication is widely prescribed because it addresses multiple symptoms in a single tablet. The tablet is safe for most patients when used in the prescribed dosage and duration.
Abibba Pharmacia develops and supplies this product under the brand name Abipan-D. It is a Chandigarh-based pharmaceutical company specializing in the manufacturing and distribution of a wide range of products. The company also offers PCD Pharma Franchise opportunities with exclusive monopoly rights for districts or states.
Mechanism of Pantoprazole and Domperidone Tablet
Pantoprazole- It reduces the amount of acid in the stomach by blocking the final step of acid production in the H+/K+ ATPase enzyme system in gastric parietal cells. It binds irreversibly to the pump and provides long-lasting acid suppression. It also helps in curing esophageal damage caused by acid reflux.
Domperidone- It acts as a Dopamine (D2) antagonist on the upper gastrointestinal tract and promotes motility. It increases the movement of the stomach and intestines and allows the food to move more easily. This reduces bloating and regurgitation. Domperidone works on the chemoreceptor trigger zone to reduce nausea and vomiting.
Benefits of Pantoprazole and Domperidone Tablets
- Provides effective relief from chest pain and acid reflux.
- Reduces the amount of acid produced in the stomach, thus preventing heartburn and indigestion.
- Increases the movement of the stomach and intestines, which helps in relieving bloating, fullness, and indigestion.
- Helps in healing gastric and duodenal ulcers as well as erosive esophagitis.
Side Effects of Pantoprazole and Domperidone Tablets
Like most medications, these capsules may cause certain effects in some individuals. These effects are generally mild and temporary and do not require any medical supervision. If symptoms persist, consult your doctor as soon as possible.
- Diarrhea
- Dry mouth
- Dizziness
- headache
Precautions of Pantoprazole and Domperidone Tablets
By following the below precautions, you will be able to achieve optimal results, as proper monitoring is required during the treatment. Awareness of safety measures is essential for everyone
- Domeperidone may increase the risk of serious, irregular heartbeats, especially in people who have or have had heart diseases, electrolyte imbalances, or those over 60.
- Prolonged use of these tablets may cause Vitamin B12 deficiency, low magnesium levels, and increased risk of osteoporosis or bone fractures.
- Inform your doctor about all the other medications that you are taking, particularly those affecting heart rhythm.
- Avoid alcohol and spicy foods, as these can worsen symptoms.
- Swallow the tablet as a whole; do not chew or crush.
- This medicine can cause dizziness, so avoid concentration tasks such as operating heavy machinery or driving.
- Inform your doctor if you have liver disease, kidney disease or a blockage in the intestine.
Frequently Asked Questions (FAQs)
Q1- Can I take pantoprazole two times a day?
A- Yes, you can take it two times a day, but under the guidance of a doctor.
Q2- Which foods should I avoid while taking pantoprazole and domperidone tablets?
A- Avoid fatty or fried foods, spicy dishes, and beverages such as tea, coffee, and cola. These can worsen symptoms.
Q3- Are pantoprazole and domperidone tablets safe for pregnancy or breastfeeding?
A- The tablets are not suggested during pregnancy, but can be taken during breastfeeding.
Q4- Do pantoprazole and domperidone tablets contain steroids?
A- No, the tablets do not contain steroids.
Q5- After how much time do pantoprazole and domperidone tablets give effective relief?
A- The tablet will take 30-60 minutes to provide relief from symptoms.
Q6- Why am I still having acidity even after taking pantoprazole and domperidone tablets?
A- If symptoms persist, then consult a doctor to know the exact cause.
Q7- Can I take pantoprazole and domperidone tablets at night?
A- Yes, you can take these tablets at night, typically 30-60 minutes before having dinner.
Q8- Do pantoprazole and domperidone tablets cause constipation?
A- While they treat acid reflux, they can cause digestive disruption, including constipation.
Q9- Can I take pantoprazole and domperidone tablets with other medicines?
A- The tablets can interact with common drugs such as blood thinners, antifungals, and HIV medicines.






