Description
Abirif 400 is the brand name for the Rifaximin 400 tablet manufactured by Abibba pharmaa. Rifaximin is a non-systemic antimicrobial agent that is used to treat infections of the gastrointestinal tract. The Rifaximin works locally in the intestine with minimal systemic absorption, which makes it safer and tolerable. The most common indications for its use are traveller’s diarrhoea, hepatic encephalopathy, irritable bowel syndrome with diarrhoea (IBS-D), and other bacterial gut infections. This medicine has a targeted mechanism of action that ensures a rapid symptom relief.
Composition of Abirif-400 tablet
Each of the medicines is formed by the active ingredients and the most effective drug
Rifaximin 400
Mechanism of Action
The rifaximin is an antibiotic that belongs to the class of Rifamycin. The working mechanism of this antibiotic is based on binding to the beta subunit of the bacterial DNA and RNA. This prevents bacterial growth and death by stopping its replication it.
Dosages and Administration
This medicine has uses in different conditions, some of which are mentioned below
- In the treatment of traveller’s diarrhoea, the recommended dose is three times daily of a 200mg tablet
- In case of Hepatic Encephalopathy, the dose is 400 mg two to three times daily as prescribed by the physician.
- In case of IBS with Diarrhoea (IBS-D), the normal dose is 400–550 mg three times daily for 10–14 days, depending on severity.
Administration
- The tablet must be taken orally with or without food
- Must complete the full course of the medication
- Only use if prescribed by the doctor; self-medication can cause serious health issues or unwanted reactions and conditions.
Possible Side Effects
Abirif-400 tablet may show some of the common side effects which are normally adapted by the body, but incase it persis,t consult your doctor as soon as possible. Some of the possible side effects of this medication are:
- Nausea or vomiting
- Abdominal pain or bloating
- Flatulence
- Headache or dizziness
- Rarely, skin rash or hypersensitivity reactions
Precautions While Using Abirif-400
To use the medicine effectively and without any unwanted side effects, we must follow some precautions such as :
- Abirif-400 is not recommended for patients with liver impairment, unless it is prescribed by the doctor
- Must avoid the prolonged use of it as it can increase the risk of bacterial resistance.
- In case of pregnancy or planning for it, you must inform your doctor
- It is not suitable for systemic infection
- If the patient has a history of antibiotic-associated colitis, use the medication cautiously
Storage Instruction
- Store the medicine in a cool and dry place
- Avoid direct contact with sunlight
- Keep out of children’s use.
Frequently Asked Questions
Q1: What conditions is Abirif-400 used for?
Abirif-400 is used for traveller’s diarrhoea, hepatic encephalopathy, and irritable bowel syndrome with diarrhoea (IBS-D).
Q2: Can Abirif-400 be taken with food?
Yes, it can be taken with or without food, but taking it with meals may improve tolerance.
Q3: Is Abirif-400 safe for children?
It may be prescribed for children above 12 years under medical supervision. For younger children, consult a paediatrician.
Q4: Can Abirif-400 be taken with alcohol?
While no direct interaction exists, alcohol should be avoided as it can worsen GI symptoms.
Q5: How soon can I expect relief after starting Abirif-400?
Symptom relief is usually observed within 24–48 hours, but completing the full prescribed course is essential.
