Description
Vildagliptin & Metformin HCI Tablets- The combination medication is used to improve glycemic control in adults with type 2 diabetes. The dual-action therapy lowers blood sugar by increasing insulin production and reducing glucose production.
It is used when metformin alone or combined with separate tablets does not provide adequate control.
Vildaplitin increases insulin production while reducing glucagon and Metformin helps the body use insulin more effectively. It helps manage blood glucose to lower the risk of kidney damage, blindness, nerve issues, and heart diseases. The tablets are recommended to take with food to minimize stomach upset.
Abibba Pharmecia manufactures these tablets under the brand name Abivil-M. The company is a leading pharmaceutical company that specializes in PCD pharma franchises and third-party manufacturing services.
Mechanism of Vildagliptin and Metformin Tablets
Vildagliptin blocks the dipeptidyl peptidase-4 (DPP-4) enzyme which breaks down GLP-1 and GIP. The increased GLP-1/GIP levels boost insulin secretion only when blood sugar is high and decrease glucagon release from alpha cells. It reduces after meal glucose levels.
Metformin decreases the amount of sugar produced by the liver. It increases peripheral tissues’ sensitivity to insulin, aiding in better glucose uptake. It decreases the amount of glucose absorbed from the gut.
The combination acts on both insulin secretion and insulin resistance.
Benefits of Vildagliptin and Metformin Tablets
The combination improves insulin action, reduces glucose production in the liver, and lowers the risk of sudden sugar spikes. It also supports better long-term diabetes management when taken as prescribed.
- A single tablet provides metabolic control and persistence.
- Long-term management with this combination helps prevent diabetes-related complications.
- Helps manage blood glucose to lower the risk of kidney damage, blindness, nerve issues, and heart diseases.
- Unlike other diabetes medicines, the combination does not promote weight gain
- It also has lower risk of causing low blood sugar.
Side Effects of Vildagliptin and metformin Tablets
However, it is a well-tolerated formulation, but it may cause minor side effects. Such reactions are temporary, do not stop taking the medicine suddenly because of this. If symptoms persist, then consult with your doctor.
- Headache
- Dizziness
- Tiredness
- Weakness
Precautions of Vildagliptin and Metformin Tablets
Vildagliptin and metformin is a prescription medication that is used in chronic management of high uric acid levels in adults. For best results, you should take this medicine with proper care and attention. Consulting a healthcare professional and following recommended precautions will ensure a safe treatment.
- Metformin can rarely cause lactic acidosis. If you suffer from persistent vomiting, stomach pain or difficulty in breathing, then consult a doctor.
- Before starting the treatment, ensure your idney function and liver enzymes are checked.
- Alcohol can increase the risk of lactic acidosis, so avoid consuming that.
- Regularly check your kidney and liver function.
- Do not use these tablets if you are allergic to vildagliptin or metformin, or you have diabetic ketoacidosis.
- Take tablets immediately after meals to reduce stomach discomfort.
Frequently Asked Questions (FAQs)
Q1- Does Vildagliptin & Metformin combination cause weight gain?
A- This combination is generally weight-neutral and does not usually cause weight gain when taken as prescribed.
Q2- Can I stop Vildagliptin & Metformin medicine once my blood sugar becomes normal?
A- No, stopping the medicine without a doctor’s advice may cause blood sugar levels to rise again.
Q3- Is vildagliptin safe for the kidneys?
A- It can be used safely in many patients, but dose adjustment and regular kidney function monitoring are needed in people with kidney problems.
Q4- Is vildagliptin safe for long-term use?
A- Yes, it is considered safe for long-term use when taken under medical supervision with regular check-ups.
Q5- Does Vildagliptin & Metformin cause vitamin deficiency?
A- Long-term use of metformin may reduce vitamin B12 levels, so periodic monitoring is recommended.
Q6- How long Vildagliptin & Metformin tablets take for this medicine to show results?
A- Improvement in blood sugar levels is usually seen within a few weeks of regular use along with proper diet and exercise.
